Age: Men over 45 years old, women over 55 years old
Gender: More frequent in males
Family story: In the first instance (mother, father, sibling), cardiovascular disease, heart attack (infarction) or sudden early death
The presence of obstructive peripheral disease (occluded leg arteries) or cerebrovascular disease (stenosis of the jugular veins) in the patient itself
Be a smoker

Hypertension (140/90 mmHg or more or receiving treatment for hypertension)
The known low HDL cholesterol of 40 mg / dL, which is good cholesterol, triggers vascular occlusion. (Note: High cholesterol level of 60 mg / dl of HDL reduces the risk of developing vascular disease.)
High LDL-cholesterol known as bad cholesterol
Diabetes Mellitus
Obesity
Still life style
Stress: A long time constant stress exposure facilitates the development of the disease.